More immune dysregulation: Sarcoidosis and chronic graft-versus-host disease after allogeneic stem cell transplant
نویسندگان
چکیده
GVHD: graft-versus-host disease HLA: human leukocyte antigen HSCTs: hematopoietic stem cell transplants INTRODUCTION Approximately 25,000 allogeneic hematopoietic stem cell transplants (HSCTs) are performed annually. Cutaneous complications are common and include a spectrum of acute and chronic graft-versus-host disease (GVHD). Mechanisms implicated in the rare development of sarcoidosis after HSCT include specific pretransplant conditioning regimens, possible donor-to-recipient transmission, genetic predisposition of sarcoidosis, and post-HSCT immune dysregulation.
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